Six fire engines and 35 firefighters and officers were called to a fire at a block of flats in Redwood Estate in Hounslow.
A first floor flat was destroyed by fire. One man left the property before the arrival of the Brigade and was treated at the scene by London Ambulance Service crews. Sadly, he later died in hospital.
The Brigade’s 999 control officers received 13 calls to the fire.
The Brigade was called at 0851 and the fire was under control at 0946. Fire crews from Feltham, Heathrow, Hayes and Southall fire stations are at the scene.
The cause of the fire is under investigation.