Four fire engines and 21 firefighters and officers were called to a fire at a flat in Wolffe Gardens, Stratford.
Part of a flat on the seventh floor was damaged by fire. There are no reports of any injuries.
The Brigade was called at 1503 and the fire was under control at 1553. Fire crews from Stratford, Leytonstone, Plaistow and Leyton fire stations attended the scene.
The cause of the fire is under investigation.