Four fire engines and around 25 firefighters were called to a fire at a terraced house in Colliers Water Lane, Thornton Heath.
Approximately half of the ground floor was damaged by fire. The fist floor also sustained some damage in the blaze. Four people left the property before the arrival of the Brigade. Two were treated at the scene and taken to hospital by London Ambulance Service crews.
The Brigade was called at 1043 and the fire was under control at 1141, Fire crews from Norbury, West Norwood, Wallington, and Croydon fire stations attended the scene.
The cause of the fire is under investigation.