Four fire engines and around 25 firefighters were called to a fire at a semi-detached house on Parkside Avenue in Bexleyheath.
The staircase was destroyed by the fire and most of the ground floor and part of the first floor were damaged. There were no reports of any injuries.
The Brigade was called at 1022 and the fire was under control by 1148. Fire crews from Bexley, Erith and Plumstead fire stations attended the scene.