Four fire engines and around 25 firefighters attended a flat fire on High Path in Colliers Wood.
Firefighters attended a fire in a second floor flat, which destroyed one room of the property and caused damaged to several other rooms. All of the occupants had left before the Brigade arrived.
The Brigade were called at 1423 and the fire was under control at 1553. Fire crews from Wimbledon, Mitcham, Sutton and Tooting attended the scene.
The cause of the fire is under investigation.