Four fire engines and around 25 firefighters were called to a fire at house on Staplehurst Road in Carshalton.
Part of the ground and first floors of a semi-detached house were damaged by fire and the roof of the building was destroyed by the blaze. There were no reports of any injuries.
The Brigade was called at 0603 and the fire was under control by 0804. Fire crews from Wallington, Sutton and Croydon fire stations attended the scene.
The cause of the fire is under investigation.