Fifteen fire engines and around 125 firefighters tackled a fire at an industrial estate on Acton Lane in Park Royal.
An industrial unit used as a kitchen furnishing sales room was destroyed by fire and the roof of an adjacent industrial unit was damaged by the blaze. Part of another industrial unit on the other side was also damaged by the fire. There were no reports of any injuries.
Station Commander Emma Carr who was at the scene said: "Crews worked hard in hot conditions to bring the fire at an industrial unit under control.
"There was heavy smoke, so locals were urged to close windows and doors and avoid the area.
"Fire crews carried out salvage operations of expensive stock and items identified by business owners."
The Brigade’s 999 Control Officers have taken 34 calls to the blaze.
The Brigade was called at 1428 and the fire was under control by 1741. Fire crews from Park Royal, Willesden, Wembley, North Kensington and Paddington fire stations are at the scene.
The cause of the fire is believed to be accidental and involved an extraction system fitted inside a spray booth.