Four fire engines and around 25 firefighters were called to a fire at a laundry on Sunbeam Road in Park Royal.
Firefighters tackled a fire in the derelict ground floor laundry where rubbish and towels were alight. There were no reports of any injuries.
The Brigade was called at 1403 and the fire was under control by 1644. Fire crews from Willesden, Wembley, Hammersmith and West Hampstead fire stations attended the scene.
The cause of the fire has been recorded as undetermined.