Six fire engines and around 40 firefighters were called to a house fire on Marlborough Road in Forest Gate.
The ground floor of a mid-terrace house was destroyed by fire. One woman was taken to hospital by London Ambulance Service crews.
Station Commander Matt Brown, who was at the scene said: "Firefighters worked quickly to bring the fire under control.
"A woman was out of the building before firefighters arrived and was treated on scene before being taken to hospital.
"Marlborough Road was closed and crews remained on scene throughout the afternoon."
The Brigade was called at 1111 and the fire was under control by 1158. Fire crews from Stratford, Plaistow, Leyton, Barking and Bethnal Green fire stations were at the scene.
The cause of the fire is believed to have involved a candle.
A London Fire Brigade spokesperson said: “Candles, incense sticks and oil burners are one of the most common causes of fire.
“It’s really important that you never leave them unattended and keep them away from anything that could catch fire such as curtains, furniture or clothes.”
• Make sure you put out any candles, incense and oil burners when you leave the room and especially before bed.
• Place candles, incense and oil burners in heat-resistant holders and placed on a stable surface where they won't be knocked over.
• Keep them away from materials that might catch fire - that's things like curtains, furniture, clothes and hair.
• Be aware that tea lights get very hot and without proper holders can melt through plastic surfaces like a TV or bath.
• Led candles can be a great alternative - they're safe even if you fall asleep or forget to blow them out.