Firefighters rescued a man and a woman from the ground floor of a house fire on Colchester Road in Walthamstow.
A small part of the ground floor of a terraced house was damaged by fire. A man and a woman were treated on scene.
The Brigade was called at 1529 and the fire was under control by 1557. Three fire engines and around 15 firefighters from Leyton, Walthamstow and Homerton fire stations attended the scene.
The cause of the fire is under investigation.