Four fire engines around 25 firefighters were called to a fire at an industrial unit on Albert Road in South Norwood.
The mezzanine floor inside a single-storey industrial unit was destroyed by fire and part of the ground floor was also damaged by the blaze. There were no reports of any injuries.
The Brigade was called at 2259 and the fire was under control by 0055. Fire crews from Woodside, Beckenham, West Norwood and Croydon fire stations attended the scene.
The cause of the fire is under investigation.