Six fire engines and around 40 firefighters were called to a fire at a pub with flats above on Greek Street in Soho.
Part of the basement of the building was damaged by the fire. Four people left the building before the Brigade arrived. There were no reports of any injuries.
The Brigade was called at 0617 and the fire was under control by 0750. Fire crews from Soho, Euston, Lambeth, Islington and Chelsea fire stations were at the scene.
The cause of the fire is under investigation.