Two people were rescued following a fire in in a block of flats in Vandome Close, Canning Town.
Six fire engines and around 40 firefighters tackled the fire. Two women were rescued from the building using smoke hoods and were taken to hospital by London Ambulance crews. A woman and child left the building before the Brigade arrived and were treated on the scene by London Ambulance crews.
A four roomed flat on the ground floor was completely destroyed.
Fire escape hoods provide members of the public with up to 15 minutes protection from four of the main fire gases (carbon monoxide, hydrogen cyanide, hydrogen chloride and acrolein) and can be worn by conscious or unconscious people. If more than 15 minutes protection is required then another hood can be given to each wearer. They do not provide oxygen but temporarily filter toxic smoke to make breathing easier.
The Brigade was called at 1208 and the fire was under control by 1351.
Crews from Stratford, East Ham, Homerton, Greenwich and surrounding stations attended the incident.
The cause of the fire is under investigation by the Metropolitan Police.