Eight fire engines and around 60 firefighters tackled a house fire on Kingston Road in New Malden.
The ground floor, first floor and roof of a mid-terraced house were destroyed by fire. Part of the fascia of a neighbouring property was also damaged by the blaze. A man left the building before the Brigade arrived and was taken to hospital by London Ambulance Service crews.
One of the Brigade's new 32-metre turntable ladders was mobilised to the scene and was used as a water tower, allowing firefighters to get water onto the fire externally.
The fire is believed to have been caused by combustible items too close to an open fire.
The Brigade was called at 0837 and the fire was under control by 1030. Fire crews from New Malden, Surbiton, Kingston, Wimbledon and surrounding fire stations attended the scene.