Four fire engines and around 25 firefighters were called to a fire at a static home on Priest Close in Hampton.
The static home was destroyed by the fire. There were no reports of any injuries.
The Brigade was called at 2147 and the fire was under control by 2259. Fire crews from Twickenham and Feltham fire stations were at the scene.
The cause of the fire is under investigation by the Brigade and the Metropolitan Police Service.