Four fire engines and around 25 firefighters were called to a house fire on Durning Road in Crystal Palace.
Most of the ground floor of a semi-detached house was damaged by the fire. A man, a woman and three children left the building before the Brigade arrived. They were treated at the scene by London Ambulance Service crews.
The cause of the fire is believed to have involved a tumble dryer.
A London Fire Brigade spokesperson said: “If your white goods start making a strange noise, don’t ignore it. If you think there’s a problem always unplug it and contact the manufacturer or a qualified repair technician.
"Most fires where white goods are the source of ignition are not down to anything you have done – so always make sure you register your appliances as you’ll be informed if any issues are identified with the product you’ve bought."
The Brigade was called at 0100 and the fire was under control by 0158. Fire crews from West Norwood, Norbury, Woodside and Forest Hill fire stations were at the scene.