Four fire engines and around 25 firefighters were called to a fire at a flat above a garage on High Street North in Manor Park.
Half of a first floor flat was damaged by the fire and a small part of the roof was damaged. There were no reports of any injuries.
The Brigade was called at 1622 and the fire was under control by 1729. Fire crews from East Ham, Stratford, Plaistow and Ilford fire stations were at the scene.
The cause of the fire is under investigation.