Six fire engines and around 40 firefighters were called to a fire at a workshop on Westwell Mews in Streatham.
A two-storey workshop was destroyed by fire. Part of the first-floor roof of an adjacent shop with flats above and part of the ground and first floors of a further property were also damaged by the blaze. There were no reports of any injuries.
The Brigade was called at 0327 and the fire was under control by 0501. Fire crews from Norbury, West Norwood and Tooting fire stations attended the scene.
The cause of the fire is under investigation by the Brigade and the Metropolitan Police Service.