Four fire engines and around 25 firefighters were called to a house fire on Greenway in Hayes.
Most of the first floor of a two storey terraced house was destroyed by fire. One woman left before the Brigade arrived.
The Brigade was called at 1910 and the incident was over by 2031. Fire crews from Hillingdon, Northolt and Hayes fire stations were in attendance.
The cause of the fire is under investigation by the Brigade's fire investigators and the Met police.