Firefighters were called to a collision involving an aircraft near Aveley Road in Upminster.
Station Commander Jeremy Davies, who was at the scene, said: “Firefighters worked with partners to release a man and a woman trapped inside a lightweight aircraft in woodland near the aerodrome.
"They were both taken to hospital by road and air ambulance crews."
The Brigade was called at 1209 and the incident was over by 1340. Six fire engines and around 40 firefighters from Hornchurch, Wennington, East Ham, Dagenham and surrounding fire stations attended the scene.