Four fire engines and around 25 firefighters tackled a flat fire on Redmans Road in Aldgate.
A self-contained ground-floor studio flat in a residential building was completely destroyed by the fire. There were no injuries reported.
The Brigade was called at 1110 and the fire was under control at 1209. Fire crews from Bethnal Green, White Chapel, Shoreditch and Homerton fire stations were in attendance.
The cause of the fire is under investigation.