Four fire engines and around 25 firefighters tackled a fire at a house on Wilkinson Way in Chiswick.
A small part of the ground floor, most of the first floor and half of the second floor of an end of terrace three-storey house was damaged by the fire. Two adults and four children were treated on scene and two of the children were taken to hospital by London Ambulance Service crews.
The Brigade was called at 0000 and the fire was under control at 0100. Fire crews from Acton, Chiswick, Ealing and Hammersmith fire stations attended the scene.
The fire is believed to be accidental.