Six fire engines and around 40 firefighters tackled a fire at a flat on Dalston Square in Dalston.
Part of maisonette flat, in a residential block under renovation, was damaged by fire. There were no reports of any injuries. Around 200 people left the building before firefighters arrived.
The Brigade was called at 0429 and the fire was brought under control by 0509. Crews from Stoke Newington, Islington, Shoreditch, Homerton and Bethnal Green fire stations attended the scene.
The cause of the fire is under investigation.