Four fire engines and around 25 firefighters responded to a house fire on Gressenhall Road in Wandsworth.
Part of the the property's roof was destroyed by the fire, and one person left the building before the arrival of the Brigade. There are no reports of any injuries.
The Brigade was first called at 2135, and the incident was under control by 2244. Firefighters from Wandsworth, Battersea, Fulham and surrounding fire stations attended the scene.
The cause of the fire is under investigation.