Firefighters were mobilised to assist police and London Ambulance Service colleagues at an incident near Hainault Underground Station.
Assistant Commissioner for Operational Resilience and Control, Pat Goulbourne, said: “Our sincere condolences are with the all those affected by this incident, particularly the family of the teenager who has died and those injured.
“Crews were immediately deployed to provide a rescue response and assist emergency service partners in treating casualties and securing the scene."
The Brigade was called at 0735 and the incident was over for firefighters by 0924. Five fire engines and a command unit from Dagenham, Walthamstow, Ilford, Romford, Hainault, East Ham and surrounding fire stations attended the scene.