Six fire engines and around 40 firefighters tackled a fire at a commercial unit on Adrian Avenue in Cricklewood.
A commercial unit was fully destroyed by fire.
One of the Brigade's 32-metre turntable ladders was used at the scene to help fight the fire from above.
Control Officers took the first of over ten calls at 1550 and the fire was under control by 1813. Crews from Hendon, West Hampstead, Willesden and surrounding fire stations attended the scene.
The cause of the fire is undetermined.