Four fire engines and around 25 firefighters tackled a fire at a block of flats on Blackfriars Road in Blackfriars.
Part of a four roomed flat on the third floor was alight.
The Brigade was called at 1449 and the fire was under control by 1541. Crews from Lambeth, Dowgate, Peckham and Soho fire stations attended the scene.
The cause of the fire is under investigation.