Four fire engines and around 25 firefighters tackled a fire on Aurelia Road in Thornton Heath.
Part of a ground floor flat in a two-storey end-of-terraced house was damaged by fire. There were no reports of any injuries.
The Brigade was called at 1620 and the fire was extinguished by 1719. Crews from Norbury and Croydon fire stations attended the scene.
The cause of the fire is under investigation.