Six fire engines and around 40 firefighters tackled a fire on Penshurst Avenue in Sidcup.
Half of one garage was damaged by fire. One further garage, one garden shed and one vehicle inside a garage were destroyed by fire. Around six people were led to safety by firefighters from neighbouring properties. There have been no reports of any injuries.
Firefighters removed and cooled one gas cylinder to an ambient temperature as a precaution as some cylinders can explode when exposed to heat.
The Brigade's Control Officers received more than 10 calls about the fire.
The Brigade was called at 1336 and the fire was brought under control by 1446. Crews from Sidcup, Eltham, Bexley and surrounding fire stations attended the scene.
The cause of the fire is under investigation.