Eight fire engines and around 60 firefighters tackled a fire at a mid terraced house converted into flats on Brookhill Road in Woolwich.
One second floor flat was destroyed by the fire and half of the roof was damaged by the fire. Around 14 people left two neighbouring properties before the Brigade arrived. One man was treated on scene by London Ambulance Service and taken to hospital.
Control Officers took the first of seven calls regarding the fire at 0352 and mobilised firefighters from Plumstead, Greenwich, East Greenwich and surrounding fire stations to the scene. The fire was under control by 0522.
One of the Brigade's 32-metre turntable ladders was used at the scene as an observation tower to help fight the fire from above.
The cause of the fire is under investigation by the Brigade and the Metropolitan Police Service.