Six fire engines and around 40 firefighters tackled a fire at a semi-detached house on Schubert Road in Putney.
Half of the second floor and a small part of the first floor were damaged by the fire. There were no reports of any injuries.
One of the Brigade's 32-metre turntable ladders was used at the scene as an observation tower to provide the Incident Commander with an aerial view of the fire.
Control Officers took the call at 2024 and mobilised crews from Wandsworth, Battersea, Fulham and Tooting fire stations to the scene. The incident was over for firefighters at 2145.
The cause of the fire is under investigation.